David Fenstermacher, PhD

David Fenstermacher, PhD

Prior to his role as VP of Bioinformatics at MedImmune, Dr. Fenstermacher was the Chief Research Information Officer for Virginia Commonwealth University (VCU), Director of Biomedical Informatics for the Center for Clinical and Translational Research, Chief Research Information Officer for the Massey Cancer Center and Professor in the Department of Biostatistics.  Previously he was the Founding Chair and Associate Professor of the Department of Biomedical Informatics at the Moffitt Cancer Center (MCC) and Chief Bioinformatics Officer for M2Gen. He has established and directed multiple informatics research programs for more than sixteen years at the University of North Carolina at Chapel Hill, the Abramson Cancer Center at the University of Pennsylvania, and The Moffitt Cancer Center. During his tenure in biomedical informatics, Dr. Fenstermacher has designed and directed the implementation of several bioinformatics and biomedical informatics distributed computing systems to support basic, translational and clinical research, including multiple institution research projects. He has also designed data management systems for more specialized projects including integrating patient-level clinical data, genomics (genome-wide association studies, massively parallel sequencing, array-based technologies) and other ‘omics data to support studies focused on cancer and other human diseases. 

Data management systems designed by Dr. Fenstermacher have included: collection and integration of subject clinical data; data quality methodologies, development of web-based forms for input, storage and retrieval of clinical and research data, customized data representations, data governance and data sharing using data warehouses and Grid technologies. Current work focuses on developing informatics resources that span the informatics continuum of Bioinformatics, Biomedical Informatics and Clinical/Medical Informatics specifically for precision medicine and health outcomes research.

Dr. Fenstermacher received his doctoral degree from the University of North Carolina at Chapel Hill. Prior to joining the fields of bioinformatics and biomedical informatics, Dr. Fenstermacher spent fourteen years as a molecular biologist/geneticist working on several projects, including phage display technologies, FISH for cytogenetic applications and transcriptional regulation of alternate splicing in mammals. His background as a bench scientist brings a unique perspective to the design of computational tools to support basic, translational and clinical research studies. Dr. Fenstermacher has held several faculty positions at the University of North Carolina, the University of Pennsylvania, the University of South Florida, MCC and VCU.