Sorena Nadaf MS, MMI

Sorena Nadaf MS, MMI

Sorena Nadaf, M.S., M.MI is Senior Vice President & Chief Informatics Officer, for City of Hope.  He serves as the Director, Center for Informatics, overseeing programs targeting Precision Medicine, Clinical and Research Informatics, Translational Bioinformatics, Data Science, & Digital Health Innovation.

Prior to joining the City of Hope in 2016, Sorena spent a decade at University of California San Francisco as CIO and Associate Director for the Helen Diller Family Comprehensive Cancer Center and UCSF's Chief Informatics Officer.  At UCSF Sorena also served as the inaugural Director of the Translational Informatics Program, where he architected a Institution wide Precision Medicine focussed Super Shared Resource, where his vision and strategies enabled the enterprise collection, exchange, and integration of distributed, multi-dimensional, and heterogeneous clinical and biomedical data, in addition to leading in the education of Applied Informatics and Healthcare IT. UCSF's infrastructure and roadmap for Cancer Registries, OMICS data management, Clinical Research and Bio-specimen Banking was a direct result of this work, not to mention systems in place supporting patient reported outcomes and electronic medical record interoperability.  While at UCSF, Sorena was instrumental in the creation and launch of the Institute for Computational Health Sciences (ICHS), where he also was Chair of its operational infrastructure, with an initial focus on a scalable enterprise-class High-Performance Compute eco-system.

Sorena was a leading figure in the Digital transformation across UCSF during his tenure, including the implementation of its first ever EMR, CTMS, LIMS, NLP, Patient Reported Outcomes, Unified Cancer Registry, Enterprise Data Warehouse, and interoperability platforms positioning UCSF well into the 21st century.   A final highlight for Sorena during his tenure at UCSF was his role on its Precision Medicine Platform Executive Committee, where the roadmap for precision based targeted care at UCSF was created. Prior to this, he spent over 12 years at Vanderbilt University as CIO and Director of Clinical and Biomedical Informatics for the Vanderbilt Ingram Cancer Center.

Today, across the City of Hope, a key focus for Sorena continues to be leadership across enterprise Precision Medicine efforts, specifically the optimization and translation of Informatics and Data Science across basic research and clinical discoveries into practical clinical applications.  The modern healthcare environment has evolved, and through Sorena's work in partnership with Dr. Larry Kwak, he has helped initiated the Inaugural  City of Hope Precision Medicine program.  Through his newly formed Center for Informatics, which includes divisions of Clinical and Research Informatics, Translational Bioinformatics, and Public Health Informatics, has designed an effective and efficient infrastructure roadmap toward the ultimate goal of translating discovery into improved clinical outcomes and care delivery.  

Sorena has spent over 20 years perfecting the development and execution of a Precision Oncology environment by combining AI, Data Science, modern system capabilities, clinical care engineering, the information-driven nature of clinical practice, research and education. A fundamental mission has always been to deliver a baseline suite of enterprise services to support the needs of translational, biomedical, and clinical research.  This has allowed him to extend on the standardization, capture, storage, and dissemination of biomedical, clinical and basic research data that can easily be securely merged, integrated, or aggregated with other data sets.

Sorena currently serves on a number of National Healthcare and Biomedical Informatics focused boards, working groups and review committees including the Editorial Boards for the Journal of Experimental Biology and Medicine: Interdisciplinary Categories in Genomics, Proteomics, and Bioinformatics, JCO Clinical Cancer Informatics Journal, Associate Editor for IEEE Computer Society – Transactions on Computers.  He serves on the Association of American Medical Colleges Group on Information Technology Resources (GIR), and over a dozen CTSA and CCSG NCI Designated Comprehensive Cancer Center External Advisory Boards.  Sorena has been active within the AACI community and a former Steering Committee board member.   Sorena was nominated and now serves on the NIH / NCI's CTAC Clinical Research Informatics Committee.  Prior to this, he co-Chaired the NCI CTMS Executive Committee for 5 years.

Finally, Sorena co-founded and led the development of “Ci4CC” – Cancer Informatics for Cancer Centers, a not-for-profit Informatics and Precision Oncology society dedicated to Applied Informatics & Digital Technology, with a special focus on every NCI-Designated Cancer Center.  Ci4CC has quickly become recognized as the nations leading applied Cancer Information Education Society, developing strategies in Personalized Medicine, OMICS, Clinical Trials, and Translational Bioinformatics.  Ci4CC has now extended its membership to dozens of community hospitals, oncology programs, Pharma, and especially Industry leading IT and Informatics organizations.  In 2017 Sorena was named as one of the top ten Healthcare CIO's to follow on social media.