Cancer Informatics Headlines and Publications

Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1

PNAS vol.110 no. 20: Lori A. Ramkissoon et al.  Pediatric low-grade gliomas (PLGGs) are among the most common solid tumors in children but, apart fromBRAF kinase mutations or duplications in specific subclasses, few genetic driver events are known. Diffuse PLGGs comprise a set of uncommon subtypes that exhibit invasive growth and are therefore especially challenging clinically.

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